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Facts about vitamin B12 Oils

What are the ingredients in vitamin B12 Oils?

The vitamin B12 oils are composed of pharmaceutical grade, GMP produced oils and surfactants that make up the Transdermoil™ oil, plus pyrogen-free heat sterilized carbon filtered water, and injection-grade vitamin B12 derivatives.

Vitamin B12 Oils are supplied in airless pumps

B12 oils are supplied in airless pumps, which insure that the product does not get contamination from outside air, or contaminating aerosols and can therefore ensure a longer shelf life. The airless containers technology has a piston in the bottom of the container that when the product is pumped it flows the contents upward ensuring that external air does not enter the pump, as such this is very different from other air-pumps, which use compressed external air to push out the contents. This enables the effective delivery of a cleaner, more pure product, with suitable protection of the light-sensitive vitamin B12 analogues.

How should vitamin B12 Oils be stored?

The storage of B12 Oils should be at room temperature (around 20-30C, 65-80F). Refrigeration is generally not required, and freezing has been shown not to disrupt the formulation or stop it working. Very high temperatures may result in degradation of the product.

How long do you need to supplement with vitamin B12?

Repairing damage caused by vitamin B12 is a long and slow process. For instance persons with extensive peripheral neuropathy may take around two years of extensive supplementation to repair the myelin sheath. Those with Pernicious Anemia, will generally require supplementation for life.

Should I shake B12 Oils before use?

No. Shaking of the B12 Oils will introduce air into the oils and this may result in "splattering" upon activation of the pump.

Are vitamin B12 Oils suitable for vegans/vegetarians?

Yes. The B12 Oils do NOT contain any animal products.

What are the natural forms of vitamin B12?

The two active forms of vitamin B12 are methyl B12 (methylcobalamin) and adenosyl B12 (adenosylcobalamin). Cyano-B12 (cyanocobalamin) and Hydoxy B12 (Hydroxocobalamin) are pro-vitamin forms of the vitamin. As such they are inactive and have to be converted to either methyl or adenosyl B12 in the body. The enzyme that does this relies upon the two active forms of vitamin B2, namely FMN and FAD. Persons who are deficient in vitamin B2 cannot convert cyanoB12 or hydroxy B12 to the two active forms of B12. Similarly persons who are deficient in Iodine, Selenium and/or Molybdenum cannot convert dietary or supplement vitamin B2 (riboflavin) into FMN and FAD. Deficiencies in any of B2/I/Se/Mo are common in persons who are B12 deficient.

Why are the vitamin B12 Oils Red?

Vitamin B12 is one of nature's amazing vitamins and has an intense red colour. Solutions of vitamin B12 are thus intensely red in colour, similar to that of Post-Box red. Each of adenosyl B12, hydroxy B12 and methyl B12 has a very slightly different shade of red.

Are B12 Oils suitable for people with sensitive skin or multiple chemical sensitivities?

Yes. The B12 Oils have been trialed by over 3000 people of different sensitivities. They are extremely well tolerated and to our knowledge NO adverse reactions to the oils have been experienced.

The B12 oils have been specifically designed so that they contain:.

Is there anyway that I can tell if I may benefit from B12?

We have put together a "symptom" form to help people determine if they are likely to be B12 deficient. The form has been designed for you to follow your progress. Contact us and we will send you the link to the form.

Is there a relationship between vitamin B2 and vitamin B12?

Yes there is. There are two enzymes involved in vitamin B12 processing that rely on one of the two active forms of vitamin B2 (FAD) for function. Lack of dietary vitamin B2, or low conversion of vitamin B2 to FAD (due to low intake of Iodine, Selenium or Molybdenum) greatly increases the consumption of vitamin B12. In addition, in conditions such as Hypothyroidism, in which less FAD is made, vitamin B12 deficiency is common. Similarly dietary lack of iodine, selenium or molybdenum can also lead to lack of functional vitamin B2 (as FAD). Deficiency of functional B2 (as FAD) can lead to vitamin B12 deficiency. Furthermore, treatment with vitamin B12 (of any form) is less than optimal in functional B2 deficiency. NB. Selenium is often supplied as selenomethionine in supplements. Experience has shown that this form of selenium is not actively incorporated into selenoproteins if a person is functionally deficient in vitamin B12. Supplemental selenium should be as sodium selenite.

Is there a relationship between folate and vitamin B12?

Yes there is. The most common dietary form of folate is 5-methyl-tetrahydrofolate (5MTHF). Normally however, 5MTHF is formed within the folate cycle and is transformed from 5,10-methylene-THF into 5MTHF by the vitamin B2 dependent enzyme MTHFR, and then enters the methylation cycle. Within the methylation cycle Methyl-Co(III)B12 loses its methyl group to homocysteine to form methionine and Co(I)B12. Methyl-Co(III)B12 can only be regenerated from Co(I)B12 in the presence of 5MTHF. Lack of dietary or supplemental forms of folate eventually leads to lack of Methyl-Co(III)B12. More information on the methylation cycle can be found at the following link.

Why have we discontinued the Hydroxy and Hydroxy/Methyl B12 products?

Hydroxy B12 (hydroxycobalamin) is not an active form of vitamin B12, but requires conversion to Adenosyl and Methyl B12 in the body before it can be used. In many people who are functionally vitamin B2 deficient they cannot do this or their ability to do this is reduced. Hence the utility of the product was questionable, and so we have discontinued it. Some people, though are of the opinion that they could tolerate hydroxyB12 but not Methyl B12. If this is the case, then one could say that the Hydroxy B12 was "safe but useless", particularly since the Hydroxy B12 would have to be converted to Methyl B12 to have any activity in the body.

Are B12 Oils only available on-line?

Yes. At present the B12 Oils are only available on-line

What is the postage policy for B12 Oils?

We aim to dispatch the product within 2-5 days of receipt of payment. We have no control over the speed of delivery once it has left the site. Once the material has been dispatched we will send you the details so that you can track your parcel. Please make sure that you have a suitable post box to receive the oils, such that the oils are secure once delivered. The Postal Costs are indicated on the drop-down menu on the Order page. Currently there are delays due to COVID-19. Once we dispatch your order you will be sent a tracking number for you to trace the delivery, as well as a web-link. You can use this code to track where your item is. Be patient, the postal system and the airlines are doing their best under very, very trying conditions..



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