Facts about vitamin B12 Oils

What are the ingredients in vitamin B12 Oils?

The vitamin B12 oils are composed of pharmaceutical grade, GMP produced oils and surfactants that make up the Transdermoil™ oil, plus pyrogen-free heat sterilized carbon filtered water, and injection-grade vitamin B12 derivatives.

How should I apply the B12 Oils?

The oils have been designed to take the active ingredient into the skin. In order to do this, a frictional force should be used, and the oils spread over an area the size of the forearm. DO NOT USE gloves.  Use the friction from the palm of the hands to apply the oils. DO NOT USE vehicles such as spoons to apply the oils. The skin should be clean, warm and dry, as too the hands of the person applying the oils.

Vitamin B12 Oils are supplied in airless pumps

B12 oils are supplied in airless pumps, which insure that the product does not get contamination from outside air, or contaminating aerosols and can therefore ensure a longer shelf life. The airless containers technology has a piston in the bottom of the container that when the product is pumped it flows the contents upward ensuring that external air does not enter the pump, as such this is very different from other air-pumps, which use compressed external air to push out the contents. This enables the effective delivery of a cleaner, more pure product, with suitable protection of the light-sensitive vitamin B12 analogues.

How should vitamin B12 Oils be stored?

The storage of B12 Oils should be at room temperature (around 20-30C, 65-80F). Refrigeration is generally not required, and freezing has been shown not to disrupt the formulation or stop it working. Very high temperatures (above 80oC) may result in degradation of the product.

How long do you need to supplement with vitamin B12?

Repairing damage caused by vitamin B12 deficiency is a long and slow process. For instance persons with extensive peripheral neuropathy may take around two years of extensive supplementation to repair the myelin sheath. Those with Pernicious Anemia, will generally require supplementation for life.

Should I shake B12 Oils before use?

No. Shaking of the B12 Oils will introduce air into the oils and this may result in "splattering" upon activation of the pump.

Are vitamin B12 Oils suitable for vegans/vegetarians?

Yes. The B12 Oils do NOT contain any animal products.

What are the natural forms of vitamin B12?

The two active forms of vitamin B12 are methyl B12 (methylcobalamin) and adenosyl B12 (adenosylcobalamin). Cyano-B12 (cyanocobalamin) and Hydoxy B12 (Hydroxocobalamin) are pro-vitamin forms of the vitamin. As such they are inactive and have to be converted to either methyl or adenosyl B12 in the body. The enzyme that does this relies upon the two active forms of vitamin B2, namely FMN and FAD. Persons who are deficient in vitamin B2 cannot convert cyanoB12 or hydroxy B12 to the two active forms of B12. Similarly persons who are deficient in Iodine, Selenium and/or Molybdenum cannot convert dietary or supplement vitamin B2 (riboflavin) into FMN and FAD. Deficiencies in any of B2/I/Se/Mo are common in persons who are B12 deficient.

Why are the vitamin B12 Oils Red?

Vitamin B12 is one of nature's amazing vitamins and has an intense red colour. Solutions of vitamin B12 are thus intensely red in colour, similar to that of Post-Box red. Each of adenosyl B12, hydroxy B12 and methyl B12 has a very slightly different shade of red.

Are B12 Oils suitable for people with sensitive skin or multiple chemical sensitivities?

Yes. The B12 Oils have been trialed by over 6000 people of different sensitivities. They are extremely well tolerated and to our knowledge NO adverse reactions to the oils have been experienced.

The B12 oils have been specifically designed so that they contain:.

• No artificial colors or dyes
• No casein
• No yeast
• No chemical additives
• No gluten
• No corn products
• No lactose
• No soy
• No pesticides
• No citric acid
• No ascorbic acid
• No preservatives
• No carnauba wax
• No nuts, peanuts, hazelnuts, walnuts, etc
• No shellfish products
• No sunflower oil
• No Olive oil
• No Canola oil
• No Peanut oil
• No Almond oil
• No sulphites
• No Nitrites
• No salicylates
• Vegan Safe
• NO PEG

Is there anyway that I can tell if I may benefit from B12?

We have put together a "symptom" form to help people determine if they are likely to be B12 deficient. The form has been designed for you to follow your progress. Contact us and we will send you the link to the form. Serum B12 levels do not predict deficiency, unless they are very low. If they are high you may have paradoxical B12 deficiency see https://b12oils.com/paradoxical.htm

Is there a relationship between vitamin B2 and vitamin B12?

Yes there is. There are two enzymes involved in vitamin B12 processing that rely on one of the two active forms of vitamin B2 (FAD) for function. Lack of dietary vitamin B2, or low conversion of vitamin B2 to FAD (due to low intake of Iodine, Selenium or Molybdenum) greatly increases the consumption of vitamin B12. In addition, in conditions such as Hypothyroidism, in which less FAD is made, vitamin B12 deficiency is common. Similarly dietary lack of iodine, selenium or molybdenum can also lead to lack of functional vitamin B2 (as FAD). Deficiency of functional B2 (as FAD) can lead to vitamin B12 deficiency. Furthermore, treatment with vitamin B12 (of any form) is less than optimal in functional B2 deficiency. NB. Selenium is often supplied as selenomethionine in supplements. Experience has shown that this form of selenium is not actively incorporated into selenoproteins if a person is functionally deficient in vitamin B12. Supplemental selenium should be as sodium selenite.

How should the oils be applied?

The oils are designed for application to the skin. They should not be taken orally (they don't taste very nice). They should be applied to clean, dry, warm skin. DO NOT USE GLOVES, as the material that the gloves are made of may dissolve and affect the product. Do not use objects such as spoons to apply the oils. These reduce the friction on application and so will reduce the uptake of the oils. Use the palm of your hand, or your fingers of the hand to apply the oils. Penetration of the oils is aided by friction, hence the advantage of using warm fingers or the palm of your hand during application. In addition, many people may develop contact sensitivity to the material in the gloves, and "think" that it is due to the product, which it is not.

Are the oils stable upon freezing

Yes, the oils can be kept indefinitely in the freezer and should be fine when they are eventually defrosted

Do we change the composition of the oils products?

Yes occasionally we do. Hence late in 2022, after some enquiries from our customers, we increased the dose of Iodide and Molybdate in those individual oils. The increase was to four times that in the ISeMo product. In early 2023, to be consistent with the 4 X Iodide and 4 x Molybdate products we increased the dose of the Selenite product to 4 X ISeMo concentration.To mark these changes we also changed the logo on the bottles, so instead of the bottles having the red oil drop centrally on the front of the bottles, we moved the drop to the top of the bottle and made the name of the product more prominent on the label. This should also help some of our more senior customers whose eyesight may not be quite what it used to be. In addition, we have performed a minor tweak on the composition of the oils, and believe that there may  be an even more rapid and efficient uptake of the oils. This should therefore help to reduce the cost to the consumers. It does, though, come with some "Cautionary" details. Hence if you have bought product before these changes, the later products may be somewhat "stronger" than before, and hence for customers that have not quite reached their optimal doses, they may experience symptoms such as those described on our depression page (https://b12oils.com/depression.htm), however, those customers who are replete in I/Se/Mo should not notice any changes, only those that are deficient.  

What is the new CP range of oils?

We are constantly trying to optimize the activity and preserve the activity of the potentially reactive Selenite, Molybdate and Iodate oils. To this end we have changed our process for these oils to reduce the possibility that the ingredients can be inactivated during the heat processing step formerly used during the oil preparation and thereby potentially developing oils that have higher relative activity and which potentially can retain their activity for longer. Customers who have not previously used the oils will notice no difference, those who have used the oils may notice a slightly higher activity of the oils. If, via this process, we manage to obtain oils with slightly higher activity and longer shelf life, this should save the customer money in the long run. The cold processing technique would also have potentially higher safety benefits to those who make the product. In-house testing, does not, however, reveal any significant difference during oil preparation.

Is there a relationship between folate and vitamin B12?

Yes there is. The most common dietary form of folate is 5-methyl-tetrahydrofolate (5MTHF). Normally however, 5MTHF is formed within the folate cycle and is transformed from 5,10-methylene-THF into 5MTHF by the vitamin B2 dependent enzyme MTHFR, and then enters the methylation cycle. Within the methylation cycle Methyl-Co(III)B12 loses its methyl group to homocysteine to form methionine and Co(I)B12. Methyl-Co(III)B12 can only be regenerated from Co(I)B12 in the presence of 5MTHF. Lack of dietary or supplemental forms of folate eventually leads to lack of Methyl-Co(III)B12. More information on the methylation cycle can be found at the following link.

Are B12 Oils only available on-line?

Yes. At present the B12 Oils are only available on-line.

Why do we not have Hydroxy B12 Oils?

HydroxyB12 is an inactive form of vitamin B12. It has to be activated by enzymes that require functional B2. If you find that you use hydroxyB12 and it has a different effect to either Adenosyl or Methyl B12, then you are most likely functionally deficient in vitamin B2 and so are not converting hydroxyB12 to Adenosyl and/or Methyl B12. For this reason we only carry the biologically active forms of vitamin B12.

What is the postage policy for B12 Oils?

We aim to dispatch the product within 2-5 days of receipt of payment. We have no control over the speed of delivery once it has left the site. Once the material has been dispatched we will send you the details so that you can track your parcel. Please make sure that you have a suitable post box to receive the oils, such that the oils are secure once delivered. The Postal Costs are indicated on the drop-down menu on the Order page. Currently there are delays due to COVID-19. Once we dispatch your order you will be sent a tracking number for you to trace the delivery, as well as a web-link. You can use this code to track where your item is. Be patient, the postal system and the airlines are doing their best under very, very trying conditions..

More information on vitamin B12

https://vitaminb12deficiency.info

Causes of vitamin B12 deficiency

https://vitaminb12deficiency.info/causes.htm

2023 Business awards

See https://www.apac-insider.com/winners/b12-oils/